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Image Search Results
Journal: Genes, chromosomes & cancer
Article Title: NFkB is activated by multiple mechanisms in hairy cell leukemia.
doi: 10.1002/gcc.22253
Figure Lengend Snippet: Figure 3. (A) RQ-PCR of selected genomic target genes in HCL and control cell lines derived from T-cell acute leukemia (T-ALL), DLBCL, and T-cell lymphoma (TCL). (B) Western blot analysis of REL, CDK6, H2AFX, and phospho-H2AFX in HCL cell lines. TUBA served as loading control. (C) Immunocytological staining of phospho-H2AFX (green) in HCL cell lines MLMA and BONNA-12 and in control cell line KM-H2 (HL). Note the strong signals in MLMA. Preparations were counterstained with DAPI (blue). White arrows indicate typical phospho-H2AFX dots in BONNA-12 and KM-H2. The black bar indi- cates the dimension representing 10mm.
Article Snippet: The following antibodies were used: alpha-Tubulin (Sigma),
Techniques: Control, Derivative Assay, Western Blot, Staining
Journal: Genes, chromosomes & cancer
Article Title: NFkB is activated by multiple mechanisms in hairy cell leukemia.
doi: 10.1002/gcc.22253
Figure Lengend Snippet: Figure 6. Schematic summary of this study, demonstrating activation of NFkB in HCL cell lines by multiple pathways including TNF-signalling, overexpression of REL, reduced expression of TNFAIP8, overexpression of CDK6, activation of the DDR, and BRAF-signalling. Overexpressed genes are indicated in red, suppressed genes in green.
Article Snippet: The following antibodies were used: alpha-Tubulin (Sigma),
Techniques: Activation Assay, Over Expression, Expressing